| Monday, December 1, 2008 |
| Home | | Away | Time |
| Liverpool | v | West Ham | 14:00 ET |
| Saturday, December 6, 2008 |
| Home | | Away | Time |
| Arsenal | v | Wigan | 9:00 ET |
| Blackburn | v | Liverpool | 9:00 ET |
| Bolton | v | Chelsea | 9:00 ET |
| Everton | v | Aston Villa | 9:00 ET |
| Fulham | v | Man City | 9:00 ET |
| Hull | v | Middlesbrough | 9:00 ET |
| Man Utd | v | Sunderland | 9:00 ET |
| Newcastle | v | Stoke | 9:00 ET |
| West Brom | v | Portsmouth | 9:00 ET |
| West Ham | v | Tottenham | 9:00 ET |
| Saturday, December 13, 2008 |
| Home | | Away | Time |
| Aston Villa | v | Bolton | 9:00 ET |
| Chelsea | v | West Ham | 9:00 ET |
| Liverpool | v | Hull | 9:00 ET |
| Man City | v | Everton | 9:00 ET |
| Middlesbrough | v | Arsenal | 9:00 ET |
| Portsmouth | v | Newcastle | 9:00 ET |
| Stoke | v | Fulham | 9:00 ET |
| Sunderland | v | West Brom | 9:00 ET |
| Tottenham | v | Man Utd | 9:00 ET |
| Wigan | v | Blackburn | 9:00 ET |
| Saturday, December 20, 2008 |
| Home | | Away | Time |
| Arsenal | v | Liverpool | 9:00 ET |
| Blackburn | v | Stoke | 9:00 ET |
| Bolton | v | Portsmouth | 9:00 ET |
| Everton | v | Chelsea | 9:00 ET |
| Fulham | v | Middlesbrough | 9:00 ET |
| Hull | v | Sunderland | 9:00 ET |
| Man Utd | v | Wigan | 9:00 ET |
| Newcastle | v | Tottenham | 9:00 ET |
| West Brom | v | Man City | 9:00 ET |
| West Ham | v | Aston Villa | 9:00 ET |
| Friday, December 26, 2008 |
| Home | | Away | Time |
| Aston Villa | v | Arsenal | 9:00 ET |
| Chelsea | v | West Brom | 9:00 ET |
| Liverpool | v | Bolton | 9:00 ET |
| Man City | v | Hull | 9:00 ET |
| Middlesbrough | v | Everton | 9:00 ET |
| Portsmouth | v | West Ham | 9:00 ET |
| Stoke | v | Man Utd | 9:00 ET |
| Sunderland | v | Blackburn | 9:00 ET |
| Tottenham | v | Fulham | 9:00 ET |
| Wigan | v | Newcastle | 9:00 ET |
| Sunday, December 28, 2008 |
| Home | | Away | Time |
| Arsenal | v | Portsmouth | 9:00 ET |
| Blackburn | v | Man City | 9:00 ET |
| Bolton | v | Wigan | 9:00 ET |
| Everton | v | Sunderland | 9:00 ET |
| Fulham | v | Chelsea | 9:00 ET |
| Hull | v | Aston Villa | 9:00 ET |
| Man Utd | v | Middlesbrough | 9:00 ET |
| Newcastle | v | Liverpool | 9:00 ET |
| West Brom | v | Tottenham | 9:00 ET |
| West Ham | v | Stoke | 9:00 ET |